Job Title: Manager Continuous Improvement and Production Support

Location: Pearl River, NY

About the Job

This combination technical-leadership role combines hands-on expertise in biologics manufacturing with strategic team management to drive operational excellence across our Flublok production processes. You will lead a team of Subject Matter Experts while providing direct technical oversight of upstream and downstream operations, ensuring GMP compliance, and spearheading continuous improvement initiatives that enhance process efficiency, yield, and quality. The ideal candidate thrives in a fast-paced, regulated environment where technical problem-solving meets people development, and where your leadership directly impacts our mission to deliver life-saving healthcare solutions to patients worldwide.

About Sanofi:

We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.

Main Responsibilities

Team Leadership & Development:

Lead, mentor, and develop a team of Subject Matter Experts across upstream and downstream manufacturing operations
Manage a Continuous Improvement team focused on process optimization and operational excellence
Coach team members on troubleshooting strategies, root cause analysis methodologies, and process improvement techniques
Foster a culture of collaboration, accountability, and continuous learning

Manufacturing Operations & Technical Oversight:

Provide technical leadership and hands-on support for Flublok drug substance manufacturing processes
Oversee upstream operations including cell scale-up, media preparation, and protein production
Oversee downstream operations including purification and buffer preparation
Ensure all manufacturing activities comply with GMP regulations and internal quality standards
Serve as a technical resource for complex process troubleshooting and deviation investigations

Continuous Improvement & Change Management:

Drive continuous improvement initiatives to enhance process efficiency, yield, and quality
Open, author, and drive change controls through completion in accordance with quality systems
Lead root cause analysis investigations using structured methodologies (e.g., 5 Whys, Fishbone, FMEA)
Identify and implement process improvements and efficiency gains across manufacturing operations

Documentation & Compliance:

Draft, review, and approve technical documents including SOPs, batch records, protocols, and reports
Ensure documentation practices meet GMP and regulatory requirements
Support regulatory inspections and audits as needed

About You

Basic Qualifications

Bachelor's degree in biology, Biomedical Engineering, Mechanical Engineering, Biological Engineering, or related scientific discipline
Master's degree preferred
7+ years of experience in biopharmaceutical manufacturing or process development, with demonstrated hands-on expertise in upstream operations (cell growth and scale-up), downstream operations (purification and buffer preparation), and analytical techniques such as chromatography.
Minimum 3+ years of people management experience.
Demonstrated experience in Pharmaceutical GMP manufacturing environments.

Technical Skills:

Process development experience in biologics manufacturing
Strong background in root cause analysis and structured problem-solving methodologies
Single Use Technology (SUT) systems and operations
Gas chromatography and analytical techniques
Media preparation and buffer preparation
Protein production processes
Cell culture and cell scale-up operations
Upstream and/or downstream biologics manufacturing

Soft Skills

Proven ability to lead, coach, and develop high-performing teams
Strong change control management experience
Excellent written and verbal communication skills
Ability to balance strategic leadership with hands-on technical support
Strong organizational and project management skills
Collaborative mindset with ability to work cross-functionally

Preferred Qualifications

Experience with Flublok or recombinant protein vaccine manufacturing
Experience with insect cell culture systems (e.g., Sf9, expresSF+)
Lean Six Sigma certification or equivalent continuous improvement training

Why choose us?

Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Shape the future of medicine and vaccine delivery with cutting-edge technology, ensuring seamless launches and a resilient global supply.
Power industry-leading performance by leveraging digital, data, and AI-driven innovation – at speed and scale
Transform lives worldwide by delivering life-changing treatments anywhere, anytime.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

$113.250,00 - $163.583,33

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.