Job Description
Job Overview:
Why Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development in gene therapy, RNA and gene editing. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:
Physical and Emotional Wellness
Financial Wellness
Support for Caregivers
For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us
The Importance of the Role
This individual provides qPCR and ddPCR assay support for on-going programs for AAV based gene therapy products. The individual will be responsible for interacting with SMEs and assisting in analytical method development, qualification, and validation activities of qPCR and ddPCR test methods supporting regulatory filings and clinical comparability. The individual will be responsible for conducting the test methods in the laboratory to support the in-process, release, stability, and investigative testing of AAV based gene therapy products.The Opportunity to Make a Difference
Perform Quantitative Polymerase Chain Reaction (qPCR) and Droplet Digital PCR (ddPCR) based test methods in support of in-process, release, stability, and investigative testing of AAV based gene therapy products.
Assist with the development, qualification, and validation activities related to viral test methods (qPCR & ddPCR) for AAV based gene therapy products intended for clinical and commercial stage programs.
Troubleshoots routine technical challenges and contributes to their resolution.
Create and maintain clear and concise lab records and documentation.
Perform other related duties incidental to the work described.
More about You
B.S. degree in Molecular Biology, Microbiology, Biology, Chemistry or related field with 0 - 2 years relevant experience.
A strong understanding of contemporary molecular biology methods with hands on qPCR experience is required.
Experience with ddPCR, liquid handling automation systems (epMotion), and QuantStudio PCR systems is useful.
Experience working in a cGMP environment is desired.
Experience in general laboratory experimentation and documentation is required.
Must have effective written and verbal communication skill and strong attention to detail.
Ability to operate as part of a team; assisting fellow lab associates in providing a functional, safe working environment while maximizing laboratory efficiency.
What Now?
We’re always looking for solution-oriented, critical thinkers.
So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
